Sassuolo vs Lazio Preview, Prediction, Possible Lineups and Betting Tips

Sassuolo are still searching for their first win of the season, as they play host to Lazio and you can find our full preview, prediction, possible lineups and betting tips below.

Sassuolo vs Lazio Preview

The Neroverdi clinched promotion back into Serie A after finishing top of Italy’s second division at the first attempt, picking up 82 points – six more than Pisa in second place.

However, Fabio Grosso’s side have been hit with a major reality check since returning to Serie A, losing both of their opening matches and sitting bottom of the table.

Sassuolo were beaten 2-0 by Napoli in a Serie A vs Serie B champions clash, as Kevin De Bruyne and Scott McTominay secured all three points away from home.

Going against the current Scudetto winners was never going to be an easy task, so fans were ready to see improvement against Cremonese in MD2 of Serie A.

However, despite a valiant effort from Grosso’s men, who came back from 2-0 down, Sassuolo conceded a 93rd minute penalty and left Cremona with nothing.

The winning penalty was scored by Manuel De Luca, who has recently been backed by fans following Jamie Vardy’s arrival and Sassuolo will now put this behind them as Grosso’s men welcome Lazio.

Maurizio Sarri’s side were hit with some terrible news in the summer transfer window, as the Laziali were penalized for failing to adhere to financial parameters and cannot sign any players until January.

The doom and gloom from the summer clearly transferred into the opening day of the season, as Lazio were beaten 2-0 by Como at Stadio Giuseppe Sinigaglia.

However, Lazio managed to overcome this disappointing result in their most recent Serie A clash, as Sarri’s men thrashed Hellas Verona 4-0 in the Italian capital.

Matteo Guendouzi, Mattia Zaccagni, Taty Castellanos and Boulaye Dia were on all target for Lazio, putting the club in a good position for their trip to Sassuolo.

Sassuolo vs Lazio Possible Lineups

Sassuolo: Muric; Walukiewicz, Idzes, Muharemovic, Doig; Vranckx, Matic, Boloca; Berardi, Pinamonti, Lauriente

Lazio: Provedel; Hysaj, Gila, Provstgaard, Tavares; Guendouzi, Rovella, Dele-Bashiru; Cancellieri, Taty Castellanos, Zaccagni

Sassuolo vs Lazio Prediction

Sassuolo’s poor start to the season means that Fabio Grosso will not be full of confidence going to Sunday’s clash against Lazio, especially after the Laziali’s 4-0 win over Hellas Verona.

Lazio may have been distracted due to links involving Lorenzo Insigne, however, the previous meetings between these two sides suggest the Lazali should find success.

The Rome-based side are unbeaten from their last five matches against Sassuolo (4W & 1D).

Taking this into consideration, we expect Maurizio Sarri’s side to pick up all-three points on September 14th and extend Sassuolo’s search for a league win.

Prediction: Sassuolo 1-2 Lazio

Sassuolo vs Lazio Betting Tips

Taty Castellanos to score at any time: 

Taty Castellanos ended the 2024/25 season as Lazio’s goal contributor, scoring 14 and assisting eight in 40 appearances across all competitions.

The Argentine has already opened his account for the 2025/26 league season, as Castellanos scored and provided two assists in the 4-0 win over Hellas Verona.

Typically, if Castellanos plays well, then Lazio do as well, so we expect the 26-year-old to be on top form against a weak Sassuolo side and score in consecutive league matches.

Sassuolo vs Lazio Odds

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